Chronic Pain Optimization and Management for Relief and Functionality with TEA in Cirrhosis: The COMFORT Pilot Proposal (NCCIH R01)
Amount
Not specified
Deadline✓ Verified
Jul 31, 2029
Funder
National Center for Complementary and Integrative Health
Eligible
open to all
About This Grant
Abstract Three of the four leading causes of years lost to disability are chronic pain conditions. Non-pharmacological interventions are widely recommended but uptake remains poor. Patients are interested but report needing evidence of effectiveness for patients like them. This problem is particularly urgent for patients with cirrhosis. Cirrhosis afflicts >2 million Americans. Chronic pain among people with cirrhosis is common and uniquely morbid with a prevalence of 40-79%. Conventional approaches to pain in cirrhosis are unsafe, ineffective, and fail to address the most common, underlying nociplastic pain type. Research on integrative therapy for chronic pain in cirrhosis is lacking. With this R01, we will achieve substantial progress. We will conduct a pilot trial of transcutaneous electrical Accustimulation (TEA) for the management of chronic pain. We have developed a novel method of TEA that substantially improves pain and other symptoms in patients with various gastrointestinal d
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