Virtual Rheum: The Development of a Virtual Mind-Body Resiliency Intervention for Patients with ANCA-Associated Vasculitis and Systemic Lupus Erythematosus (NCCIH R34)
Amount
Not specified
Deadline✓ Verified
Aug 31, 2029
Funder
National Center for Complementary and Integrative Health
Eligible
open to all
About This Grant
PROJECT SUMMARY People with ANCA-associated vasculitis (AAV) and Systemic Lupus Erythematosus (SLE), two prevalent and impactful types of systemic autoimmune rheumatic diseases (SARDs), live with relapsing autoimmune disease that can affect nearly any organ, requiring years of close monitoring and immunosuppression, all of which contribute to unique sources of chronic daily stress. Sources of stress in SARDs include internal stimuli related to the toxicities of treatment (e.g., weight gain, fat redistribution, insomnia from steroids) and consequences of the disease and the damage it causes (e.g., pain, fatigue). External stimuli include the uncertainty regarding the risk, timing, and impacts of a relapse, as well as the risks of severe infection with long-term immunosuppression. This chronic stress contributes to poor outcomes for patients with SARDs and related conditions, including worse mental and physical health and greater disability. Despite tremendous advances in immune-targeted
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