Modeling of inter-individual differences in chronic pain using holistic measures of pain SEveRity, strEss, cogNITion, bodY and mind awareness (SERENITY) (NCCIH R01)
Amount
Not specified
Deadline✓ Verified
May 31, 2031
Funder
National Center for Complementary and Integrative Health
Eligible
open to all
About This Grant
PROJECT SUMMARY In the U.S., 21% of the population suffers from chronic pain, with chronic low back pain (cLBP) being one of the most common, and chronic neuropathic pain affecting 69% of those with a spinal cord injury (SCI). The bi- opsychosocial chronic pain model points to additional variables accompanying chronic pain, e.g., pain interfer- ence on function, which is a clinically meaningful outcome. However, the between-subject heterogeneity of pain interference has not been identified. In addition, the correlational or the causal relationships between ho- listic variables accompanying chronic pain, and pain interference have not been investigated. Our premise is that without this information on person-specific holistic variables associated with or causing pain interference, treatment selection is unfocused, non-specific, and may limit effectiveness. Identifying person-specific varia- bles associated with or causing pain interference, using NIH HEAL core pain domains, is a critical
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